View Full Version : glucogenesis

irish mike
03-10-2002, 06:07 AM
does anyone know if the chemical structure of glucose produced from glucogenesis is different than normal glucose.in theory if its not, glucose from protein replenishing muscle glycogen sounds like it has the potential to be anabolic doesn't it?does anyone understand what i'm getting at?

03-10-2002, 06:27 AM
glucose - will always be the same strucutre. otherwise it would be glucose. it would have a different name.

glucogenesis from protien would not anabolic as the protien is not being used for tissue building.

03-10-2002, 07:38 AM
Glucose is transported in the blood in the unaltered form - upon uptake by the body's cells, glucose is typically phosphorylated (by an enzyme called glucose-6-kinase) which in lay terms helps the cell keep the glucose from leaving before it is used. Gluconeogenesis, as the name implies, is the manufacture/creation (genesis) of glucose (gluco) de novo/new (neo). Gluconeogenesis does not imply glucose derived from the breakdown of glycogen (the metabolic pathways are different) which is called glycogenolysis. The substrates for gluconeogenesis are many however some typical source materials for this process are pyruvate, lactate, and amino acids (but not fatty acids - hence the ketogenic pathways mentioned in many diet plans on this forum). If the body is having to utilize amino acids for gluconeogenesis it is catabolizing proteins and therefore is unlikely to support an enviroment in which muscle growth (muscle building - anabolism) will occur.