Why Cycle ECA?

[Frozenmoses]

I'm just wondering what the reason is for cycling ECA. Is it because of potential heart problems? Does the stack become less effective with prolonged use? Any input appreciated.

[Mik]

Your body becomes used to it rendering it less effective.

[IceRgrrl]

Yes, what Mik said...your body builds up a tolerance to it over time. But then there is some evidence that ECA has a marked effect on certain types of fat only after prolonged use, so it's a toss-up.

[The_Chicken_Daddy]

If you use it for energy boosts, pre-workout, for example, then cycle it so you still get the 'wired' effect.

As far as fat burning goes, there's no need to cycle it. One study lasting about 8 months showed that it actually gets better with continuous use for this reason. I've not seen it myself, but i've heard from two extremely reliable sources.

You may lose the jitteriness and wired feeling, but the fat burning aspect of it is still present.

[Frozenmoses]

Wow, okay. Thanks for the responses. I'd actually prefer getting rid of the wired effect. I guess I'll stay on throughout my entire cutting cycle. Again, I appreciate it.

[Holto]

Originally posted by The_Chicken_Daddy
One study lasting about 8 months showed that it actually gets better with continuous use for this reason.

I have also seen a study like this...

part of the reality is that you can't calorie restrict for ever and you need to come off a DIET now and then to restabilize your metabolism...

when you do that you may as well stop eca...

so when weight loss stops, stop dieting and then stop the eca and then go back at it

[drak]

I used to take ECA all the time, but it stopped doing much for me. What really helped was rotating it every 3-4 weeks with NYC. It makes a huge difference and I dont get non-functional for a couple of days and weak for couple of weeks, which is what happened why I just went off. For a nice change I throw in some clen occasionally.

But when I bulk I only use ECA before my workouts and just have caffeine through the day. I am just too busy with work to be tired.

[Shankerr]

Its a good idea to give the ephedrine receptors in your body a lil rest from tiem to time, thats why cycling is a good idea.. You'll notice after a while that you don't get as jittery and hyper, thats because the receptors are being blocked... if you cycle off for a bit, give your bodt a rest, then hit it up again, you'll be back, wired as ever!

[The_Chicken_Daddy]

Originally posted by Shankerr
Its a good idea to give the ephedrine receptors in your body a lil rest from tiem to time, thats why cycling is a good idea.. You'll notice after a while that you don't get as jittery and hyper, thats because the receptors are being blocked... if you cycle off for a bit, give your bodt a rest, then hit it up again, you'll be back, wired as ever!


Ephedrine receptors?

Receptors being 'blocked'?

Sorry man, but you need to do some reading.

[MemphisRAGe]

LOL!!!!!!:withstupi

[Shankerr]

take some biology. do you know what receptors are, or how they work?

[Shankerr]

Oh, Chicken Daddy, just for a lil bit of additional info.. (not meant as a flame, even though thats what you did to me).....

Ephedrine shows signs that it has A1, A2, B1 and B2 andregenic receptor-agonist properties. i.e.... It gets its thermogenic properties by activating Beta1 and Beta2 receptors (and Alpha1 receptors I believe), which then release noradrenaline. This noradrenaline, as you know, causes your body to produce a fight or flight response, which raises heart rate, blood pressure, etc.. (ie, thermogenic qualities)

questions??

[The_Chicken_Daddy]

Yes, they're called adrenoreceptors - not 'ephedrine receptors'.

And these receptors don't release adrenalin and noradrenalin - the synaptic cleft does. Once released, the NA stimualtes ALL adrenoreceptors - all alpha and all Beta - it ain't selective.

At lower thresholds it stimulates the a-receptors mostly (the a-receptors suppress lipolysis) but at higher thresholds (i.e. once stimulated by something like ephedrine) they stimulate the b-receptors (which promote lipolysis).

But that aside, the receptors aren't 'blocked'. In fact, if anything, over time they receptors upregulate (there's various theories for this). Just because the jitteriness has gone doesn't mean the fat burning quality has gone. If you want EC for energy then cycle it. If you want it for fat loss assistance then there's no need to cycle it.

And to clarify, i wasn't flaming you at all. It's my style of writing. However, having "questions??" at the end of your post was a flame.

[Shankerr]

nah dude, wasn't falming on that one. I was asking ya if you wanted me to clarify anything.. apparently you've taken the same pharmacology classes I have, which is cool! :)

Now from what I have heard, effective lipolysis is still shown to be in effect on EC even a full year after starting, with no breaks. However, I think that it was also shown that after a long period of exposure to a chemical like alpha-[1-(Methylamino)ethyl]benzene-methanol, the sympathetic neurons won't release NA as readily as they will for say the first 10 weeks of exposure..

Edit: Which was kind of what I was aiming at in the first post, just got sidetracked a bit...

[Shankerr]

ps. where did you do your pharm??

and i am sorry if ya thought I was flaming ya, its just the way I write too, no hard feelings?

[The_Chicken_Daddy]

Originally posted by Shankerr
nah dude, wasn't falming on that one. I was asking ya if you wanted me to clarify anything.. apparently you've taken the same pharmacology classes I have, which is cool! :)

Now from what I have heard, effective lipolysis is still shown to be in effect on EC even a full year after starting, with no breaks. However, I think that it was also shown that after a long period of exposure to a chemical like alpha-[1-(Methylamino)ethyl]benzene-methanol, the sympathetic neurons won't release NA as readily as they will for say the first 10 weeks of exposure..


Well, that's known as 'adrenal exhaustion', if anything.

The longest studiy i'm aware of using EC is 8 months. And it was still efficient then.

P.s. Can we stick to the basic name for the compound - a lot of people are gonna look at that and think "What the fuk?!"

No pharm classes or degrees. All i know is what i've took the liberty to learn in my free time. :)

Well, except maybe a brief biochemistry module in my biology A-level (one step down from a degree), but all i really covered in that was water, lipids, proteins and saccharides. And a bit of genetics and DNA.

[Shankerr]

Nice, its good to see that someone other than me takes the time to find out about what they're putting into their bodies before they just suck back a bottle of pills! :)

[Frozenmoses]

Wow, there's lots of smart people talk in my thread. Does that make me smart by association?

[Belial]

No, it doesn't. *pat pat*

You'll get 'em next time, slugger.

[Frozenmoses]

Damn.

[Brahms]

Originally posted by The_Chicken_Daddy
And these receptors don't release adrenalin and noradrenalin - the synaptic cleft does. Once released, the NA stimualtes ALL adrenoreceptors - all alpha and all Beta - it ain't selective.


Actually. the release of Adrenalin occurs via exocytosis from the presynaptic terminal. Adrenaline hormone molecules flow across the synaptic cleft and reach the receptors on the postsynaptic cell. And there is some new studies out that indicate that the adrenaline receptors may, in fact, be selective towards Beta cells, but the mechanism by which this occurs is unclear.

[The_Chicken_Daddy]

Originally posted by Brahms


Actually. the release of Adrenalin occurs via exocytosis from the presynaptic terminal. Adrenaline hormone molecules flow across the synaptic cleft and reach the receptors on the postsynaptic cell. And there is some new studies out that indicate that the adrenaline receptors may, in fact, be selective towards Beta cells, but the mechanism by which this occurs is unclear.

Bah! Same difference. lol.


How new is/are the study(ies)?

I've never read anything about that. Must be pretty frickin' recent.

[Brahms]

Actually, I don't know what research the preference for B-receptor comes from. I do remember the Teaching Assistant telling us this in my Physiology class last week. Geez! I really need to quit dozing off in that class. :D