Cycle Ephdrine

[kozen]

Am i suppose to cycle my ephedrine/caffine stack? I take 1 capsule (25 mg) pre work out, about 3-4 times a week. Ive been on it for 8 weeks.. any help would be appreciated

[Podium Kreatin]

imo, its pretty hard to becoem dependent on ephedrine (caffeine does not cause dependency). as long as u dont' use it everyday of the week (which is not ur case, 3-4x/week), i think thats' good enough to maintain the potency of ephedrine.

i'll try to draw out the pathways to support my arguement:
1) epinephrine->beta-receptor-> g-alphaprotein-> AC -> cAMP-> PKA-> phosphorylation of beta-receptor
2) epinephrine->beta-receptor-> g-beta-gamma protein-> BARK -> arrestin

arrestin will destroy beta-receptors phosphorylated by PKA. thisis a normal feedback mech, and happens all the time, say, when u are running away from a bear, or get nervous when u try to approach a hot chick. ephedrine is an epinephrine-analog, and will go through the same pathways. after a period of time, ur body will make beta-receptors again when the epinephrine/ephedrine disappears from the blood. so, imo, one/two days w/o using ephedrine is sufficient as a "cycle" b/c ur body regenerates the receptors pretty quickly

caffeine doesn't have any feedback mechanisms (u can take more and more, and it will get stronger and stronger. the limit to the potency of caffeine is when u take so much that u die), so, if u are taking caffeine pills separate from the ephedrine, then u dont' have to cycle this

[Saint Patrick]

Well apparently your body builds up a tolerance after a while, and the fat burning effects aren't as strong.

Perhaps stop for a couple weeks, but then again you're only taking one dose 3/4 times per week, so you may not build up a tolerance like people like me, who take it 2/3 times every day when cutting.

[Shao-LiN]

Well apparently your body builds up a tolerance after a while, and the fat burning effects aren't as strong.

Perhaps stop for a couple weeks, but then again you're only taking one dose 3/4 times per week, so you may not build up a tolerance like people like me, who take it 2/3 times every day when cutting.

You sure about that? All the articles I have read point to your body building up a tolerance to the stimulant effects of ephedrine, but chronic use improves the efficacy of ephedrine's fat burning properties.