question about injections and ARs

[SpecialK]

You inject into a muscle, not into a vein, correct? How then does the substance you injected get to all parts of your body to exert its influence on other muscles? It sounds like a dumb question but I was under the impression that in someone who isn't using gear, the test that initiates the muscle building process is in your bloodstream.

Also, what is an androgen receptor? I know you want the test or whatever substance to bind to it, but where are they located? In muscle cells?

[restless]

You inject into a muscle, not into a vein, correct? How then does the substance you injected get to all parts of your body to exert its influence on other muscles? It sounds like a dumb question but I was under the impression that in someone who isn't using gear, the test that initiates the muscle building process is in your bloodstream.

Also, what is an androgen receptor? I know you want the test or whatever substance to bind to it, but where are they located? In muscle cells?


As the hormone get's released from the ester it does go into your veins. I don't know much about the ester breakdown process but the hormones do get into your bloodstream.


The androgen receptor is a protein that exists in different tissues inside the cells. It's quantity vary by means of half life regulation and it's activation by compounds with AR afinity results in the activation of different genes that do different things in different tissues. Pretty much all I know about this. I find It kind of complicated.

[BCC]

Yes, as the ester is hydrolized it releases the hormone into the blood stream where it is picked off by ARs. An ester lowers the water solubility of the hormone and raises its fat solubility. So it forms a deposit in the muscle tissue which is slowly drawn away by the blood. The rate of this is dependent upon the degree of solubility.

[thetopdog]

You probably already know this but, DON'T inject into the veins thinking that it will make the drug enter the bloodstream more quickly, injecting steriods into a vein can kill you

[SpecialK]

You probably already know this but, DON'T inject into the veins thinking that it will make the drug enter the bloodstream more quickly, injecting steriods into a vein can kill you

Thats just because of the oil they are suspended in, right?

[BCC]

Yes and it just isn't how they were intended to be used.

[chris6969]

Ok, someone's been reading that other thread... about that idiotic article from that guy where we were all joking about sharing needles and IV shots.

[Beast]

inject -> bolus -> bloodstream -> receptors