View Full Version : "LDL Cholesterol: 'Bad' Cholesterol, or Bad Science?"

02-22-2006, 07:17 PM
I found this study interesting and wanted to know what others' thoughts were on it:


02-22-2006, 07:56 PM
i read about half of it, and it was a great example of how to use strawmen, misleading implications, false dillemas, etc.

02-23-2006, 01:04 PM
Yeah? How so?

02-23-2006, 01:59 PM
Yeah so they have found a more defined "bad cholesterol" its oxidized LDL.

In Japanese patients undergoing surgery to remove plaque from
their carotid arteries, blood levels of oxidized LDL were
significantly higher than those measured in healthy controls.
Advanced carotid plaques removed from these patients showed far
higher levels of oxidized LDL than neighboring sections of artery
that were disease-free. Elevated oxidized LDL was also associated
with an increased susceptibility of plaque rupture. However, there
was no association between oxidized LDL concentrations and total

This I feel is much more interesting. Most of us take a bunch of fish oils per day.
Von Shacky and coworkers, in a 2-year double-blind trial in
patients with CHD, found that daily fish-oil supplementation
increased the incidence of atherosclerotic regression, and
decreased the loss in minimal luminal diameter, as assessed by
quantitative coronary angiography. Fish-oil recipients also
experienced fewer cardiovascular events. LDL cholesterol levels
tended to be greater in the fish-oil group.

According to common wisdom, the lower total and LDL
cholesterol of the Lithuanian men should have placed them at
reduced risk of heart disease. When the researchers probed further,
they discovered that the men from Vilnius had significantly higher
concentrations of oxidized LDL. They also displayed
significantly poorer blood levels of important diet-derived
antioxidants such as beta carotene, lycopene, and gamma
tocopherol (a form of vitamin E). Blood levels of these particular
nutrients are largely determined by dietary intake, especially from
the consumption of antioxidant-rich fruits, nuts, and vegetables. So
while the Lithuanian men had lower LDL levels, they were more
prone to the formation of oxidized LDL owing to what appeared to
be a poorer intake of antioxidant-rich foods.

Wow, that pretty much sums it up. This article was very interesting, yes it seems to claim that LDL isn't the problem. But, it does show the its a form of LDL (oxidized LDL) that is the helpds plaque form. What I think this article really pointed out best is how important antioxidents, omega 3's, and 6's are to our health. And, not only our health but possibly help reduce the our risk of CHD.

08-22-2012, 10:15 AM
This is an interesting report by Anthony Colpo. Having said that, I do believe his conclusion could have been more powerful given the evidence he lays out--and the evidence is remarkably written.