View Full Version : Research on long term protein supp use

07-19-2006, 04:43 PM
I take approx 150g whey protein daily, sometimes 200g (ON whey). Just wondering if there are negative side effects of this, eg. kidney stress etc, and if anyone know of any research into this?

Im asking because friends and family seem overly concerned that im taking 'so much' protein, and they seem convinced its unhealthy... :boring: So im looking for some evidence to back me up in my arguments really!

Is it ok to use it daily, long term, i.e a year plus?

Any links to published research would be appreciated! Thanks!

07-19-2006, 04:45 PM
How much protien do you get daily?

07-19-2006, 04:49 PM
How much protien do you get daily?

I'm pretty sure that was stated in the first sentence of his post. Or do you mean TOTAL protein, not just the whey?

07-19-2006, 04:50 PM
um.... first sentence!!!

07-19-2006, 05:07 PM
The protein comes from eggs, milk, etc. Unless there is a side effect to long term use of eggs, then I think it's ok. A high protein diet, however, does make you slightly more suceptible to kidney stones. I'm not sure what is considered "high", though.

07-20-2006, 01:01 AM
Your going to be hard pressed to find those types of studies dealing with healthy individuals. But since you asked for simply a year plus I can give you a case study. . me. I have taken 300-450 grams of protein from whey a day for over a year. Before that I was taking in around 200+ grams a day from whey (usualy well over 500g a day total protein).

I have had blood tests done and my kidneys are A-ok.

If you have a pre-existing condition then it may be something to be concerned about, but if not, I would worry more about polution.

07-20-2006, 02:14 AM
I am not sure whether you are concerned about eating too much protein or taking too much whey protein specfically, but here are some studies to lay your mind at rest in the case of the former.


Although excessive protein intake remains a health concern in individuals with pre-existing renal disease, the literature lacks significant research demonstrating a link between protein intake and the initiation or progression of renal disease in healthy individuals. More importantly, evidence suggests that protein-induced changes in renal function are likely a normal adaptative mechanism well within the functional limits of a healthy kidney. Without question, long-term studies are needed to clarify the scant evidence currently available regarding this relationship. At present, there is not sufficient proof to warrant public health directives aimed at restricting dietary protein intake in healthy adults for the purpose of preserving renal function.


Concerns that diets high in meat protein may have deleterious effects on renal function and bone turnover were not substantiated by this study, which showed similar reductions in creatinine clearance with both dietary patterns as a consequence of body mass change. Skov et al (21) assessed changes in renal function by measuring the glomerular filtration rate during high-protein and high-carbohydrate diets over a 6-mo period and also concluded that the HP diet had no adverse effects on kidney function.


CONCLUSION: Moderate changes in dietary protein intake cause adaptive alterations in renal size and function without indications of adverse effects.


Excess protein and amino acid intake have been recognized as hazardous potential implications for kidney function, leading to progressive impairment of this organ. It has been suggested in the literature, without clear evidence, that high protein intake by athletes has no harmful consequences on renal function. This study investigated body-builders (BB) and other well-trained athletes (OA) with high and medium protein intake, respectively, in order to shed light on this issue. The athletes underwent a 7-day nutrition record analysis as well as blood sample and urine collection to determine the potential renal consequences of a high protein intake. The data revealed that despite higher plasma concentration of uric acid and calcium, Group BB had renal clearances of creatinine, urea, and albumin that were within the normal range. The nitrogen balance for both groups became positive when daily protein intake exceeded 1.26 g.kg but there were no correlations between protein intake and creatinine clearance, albumin excretion rate, and calcium excretion rate. To conclude, it appears that protein intake under 2. 8 g.kg does not impair renal function in well-trained athletes as indicated by the measures of renal function used in this study

07-20-2006, 02:23 PM
These are the long term side effects -



07-20-2006, 03:17 PM
...and um...



07-20-2006, 03:34 PM
^^ and steroids. Lots of steroids.

07-20-2006, 04:09 PM
cheers everyone!

I dont really have any worries about taking large amounts of protein daily, I mainly wanted some evidence to back me up whenever im trying to explain to people that taking whey supplements is not 'unhealthy' and 'bad for you' which i seem to be hearing a lot these days from friends and family!

So, thanks for those articles people, they are interesting, and good amunition for further debates next time someone tells me how unhealthy im being by eating protein and lifting weights!

...oh and i knew some of you would start posting pics of arnie as possible 'side effects'!!! :zipit:

07-20-2006, 10:26 PM
It might be a good idea to have your blood tested every 6 months or so to make sure creatinine and BUN levels are within the normal range. I had mine checked a month ago and they were very high. Since then Ive cut back from 250-300g protein to 175-225gs (I weight 175lbs. btw). The creatinine and BUN levels dropped and Ive actually seen slightly better gains since more cals are coming from carbs and fats now.

07-20-2006, 10:32 PM
um.... first sentence!!!

Um... so your saying you get all your daily protein from protein shakes then?

07-20-2006, 11:32 PM
^^ and steroids. Lots of steroids.And steroids are nothing without food...and protein.

07-21-2006, 08:26 AM
arnold claimed that he only used steriods to retain his muscle mass when he was going on a cut. I sorta doubt that but o well, hes still the man

07-21-2006, 09:00 AM
arnold claimed that he only used steriods to retain his muscle mass when he was going on a cut. I sorta doubt that but o well, hes still the man

Only sorta? lol

07-23-2006, 06:36 PM
Only sorta? lol

oops what was that non real word doing in my sentence!?

07-23-2006, 07:44 PM
And steroids are nothing without food...and protein.