Effects of soy protein on levels of remnant-like particles cholesterol and vitamin E in healthy men.
Higashi K, Abata S, Iwamoto N, Ogura M, Yama****a T, Ishikawa O, Ohslzu F, Nakamura H.
First Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
We determined the effects of soy protein isolate (SPI) intake on
remnant-like particles (RLP), lipolytic enzymes, lipid transfer protein, transaminases, sex hormones
, iron, calcium, and vitamin E in healthy men. In the first randomized, crossover experiment, 14 men were given either 20 g per day of SPI or nothing (control) for each 4-week segment. After 3 weeks of SPI intake, TG and RLP cholesterol levels were significantly lower than the baseline by 13.4% (p<0.05) and 9.8% (p<0.05), respectively. However, no significant change was found in total and low-density lipoprotein (LDL) cholesterol levels or the activities of lipoprotein lipase, hepatic lipase, cholesteryl ester transfer protein, and lecithin cholesterol acyltransferase. Although the levels of
, iron, and calcium did not change
, the vitamin E level was reduced from the baseline by 9.7%, a significant decrease (p<0.01)...