i always see people advocating compound lifts because of the hormone response you get from them

i also see people saying that it is debatable weather or not that response is useful

at any rate if we, for arguments sake, take the hormonal response out of the equation is there any reason why a routine that is comprised of mainly compound lifts is any better than one that is mainly isolation lifts if the volume for each muscle is about the same?

assuming that your goals are body building.